Facile and selective N-alkylation of gentamicin antibiotics via chemoenzymatic synthesis
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DOI: 10.1039/d2gc03600b
Abstract: The rise and spread of antimicrobial resistance has necessitated the development of novel antimicrobials which are effective against drug resistant pathogens. Aminoglycoside antibiotics (AGAs) remain one of our most effective classes of bactericidal drugs. However,… read more here.
Keywords: step; facile selective; synthesis; selective alkylation ... See more keywords