PARP inhibitors protect against sex- and AAG-dependent alkylation-induced neural degeneration
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DOI: 10.18632/oncotarget.19844
Abstract: Alkylating agents are commonly used to treat cancer. Although base excision repair (BER) is a major pathway for repairing DNA alkylation damage, under certain conditions, the initiation of BER produces toxic repair intermediates that damage… read more here.
Keywords: parp inhibitors; mice; alkylation induced; alkylation ... See more keywords