Ruthenium(II)-Catalyzed Ortho-C-H Alkylation of Naphthylamines with Diazo Compounds for Synthesis of 2,2-Disubstituted π-Extended 3-Oxindoles in Water.
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DOI: 10.1021/acs.orglett.0c01811
Abstract: Ruthenium(II)-catalyzed ortho-C-H alkylation of naphthylamines with diazo compounds for the synthesis of 2,2-disubstituted π-extended 3-oxindoles has been developed. The method represents the first example of C-H alkylation via carbenoid insertion in water as a sustainable… read more here.
Keywords: catalyzed ortho; naphthylamines diazo; alkylation naphthylamines; alkylation ... See more keywords