Visible Light-Driven C4-Selective Alkylation of Pyridinium Derivatives with Alkyl Bromides.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c04499
Abstract: Reported herein is a general strategy for the photochemical cross-coupling between N-amidopyridinium salts and various alkyl bro-mides under photocatalyst-free conditions, granting facile access to various C4-alkylated pyridines. This approach exploits the intri-guing photochemical activity of… read more here.
Keywords: alkylation pyridinium; selective alkylation; visible light; driven selective ... See more keywords
Bromide-mediated, C2-selective, and oxygenative alkylation of pyridinium salts using alkenes and molecular oxygen.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d2cc06138d
Abstract: Herein, we report a bromide-mediated, C2-selective, and oxygenative alkylation of pyridinium salts using alkenes and O2 for the synthesis of important β-2-pyridyl ketones. Notably, a quaternary carbon center was successfully installed at the C2-position of… read more here.
Keywords: oxygenative alkylation; alkylation pyridinium; mediated selective; bromide mediated ... See more keywords