Electro-oxidative C–H alkylation of quinoxalin-2(1H)-ones with organoboron compounds
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DOI: 10.1039/d0gc03892j
Abstract: Radical cleavage of C–B bonds to accomplish C–H functionalization is synthetically appealing but practically challenging. We report herein a mild electro-oxidative method for efficient C–H alkylation of quinoxalin-2(1H)-ones by means of radical addition reactions of… read more here.
Keywords: quinoxalin ones; oxidative alkylation; alkylation quinoxalin; electro oxidative ... See more keywords
Photoinduced ligand to metal charge transfer enabling cerium mediated decarboxylative alkylation of quinoxalin-2(1H)-ones.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc00840h
Abstract: Here, we report the cerium-mediated decarboxylative alkylation of quinoxalin-2(1H)-ones utilizing feedstock carboxylic acids as a radical precursor via photoinduced-LMCT. This operationally simple protocol overcomes the limitation of the direct use of carboxylic acids to access… read more here.
Keywords: cerium mediated; alkylation quinoxalin; decarboxylative alkylation; quinoxalin ones ... See more keywords
Regioselective C-3-alkylation of quinoxalin-2(1H)-ones via C–N bond cleavage of amine derived Katritzky salts enabled by continuous-flow photoredox catalysis
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DOI: 10.1039/d2ra00753c
Abstract: An efficient, transition metal-free visible-light-driven continuous-flow C-3-alkylation of quinoxalin-2(1H)-ones has been demonstrated by employing Katritzky salts as alkylating agents in the presence of eosin-y as a photoredox catalyst and DIPEA as a base at room… read more here.
Keywords: katritzky salts; alkylation quinoxalin; quinoxalin ones; continuous flow ... See more keywords