Crossiellidines A-F, Unprecedented Pyrazine-Alkylguanidine Metabolites with Broad-Spectrum Antibacterial Activity from Crossiella sp.
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DOI: 10.1021/acs.orglett.3c01088
Abstract: Crosiellidines are intriguing pyrazine-alkylguanidine metabolites isolated from the minor actinomycete genus Crossiella. Their structures present an unprecedented 2-methoxy-3,5,6-trialkyl pyrazine scaffold and uncommon guanidine prenylations, including an exotic O-prenylated N-hydroxyguanidine moiety. The novel substitution pattern of… read more here.
Keywords: alkylguanidine metabolites; antibacterial activity; pyrazine alkylguanidine; spectrum antibacterial ... See more keywords