The Behavior of (cyclic-alkylidene)hydrazinecarbothioamides in Cyclization with Dimethyl acetylenedicarboxylate
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Heterocyclic Chemistry"
DOI: 10.1002/jhet.2803
Abstract: A series of (Z)-methyl 2(Z)-3-substituted-2-(cycloalkylidenehydrazono)-4-oxothiazolidin-5-ylidene)-acetate derivatives were synthesized via condensation alkylidene-N-substituted hydrazinecarbothioamides with dimethyl acetylenedicarboxylate. The synthesized compounds were characterized by using different spectroscopic methods and confirmed by single crystal X-ray analysis. The behavior of… read more here.
Keywords: alkylidene; behavior cyclic; hydrazinecarbothioamides cyclization; alkylidene hydrazinecarbothioamides ... See more keywords
Asymmetric Synthesis of α-Alkylidene-β-Lactams through Copper Catalysis with a Prolinol-Phosphine Chiral Ligand.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b00276
Abstract: A copper/prolinol-phosphine chiral catalyst enabled the one-step synthesis of chiral α-alkylidene-β-lactams. Optimization of the chiral ligand for steric and electronic properties realized the highly enantioselective coupling of nitrones and propargyl alcohol derived alkynes. The resulting… read more here.
Keywords: phosphine chiral; alkylidene; alkylidene lactams; prolinol phosphine ... See more keywords