Alkylidene Carbene from Silyl Vinyl Iodide Provides Mechanistic Insights on Trimethylenemethane Diyl-Mediated Tandem Cyclizations.
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DOI: 10.1021/acs.orglett.2c01622
Abstract: We describe a method to generate alkylidene carbenes via tetramethylammonium-fluoride-induced desilylation of silyl vinyl iodides. The reversible carbene generation from an iodovinyl anion enabled us to unearth mechanistic aspects of the trimethylenemethane (TMM) diyl cyclization… read more here.
Keywords: carbene silyl; alkylidene carbene; silyl vinyl; diyl ... See more keywords