C-H Activation and Alkyne Annulation via Automatic or Intrinsic Directing Groups: Towards High Step Economy.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical record"
DOI: 10.1002/tcr.201700024
Abstract: Direct transformation of carbon-hydrogen bond (C-H) has emerged to be a trend for construction of molecules from building blocks with no or less prefunctionalization, leading high atom and step economy. Directing group (DG) strategy is… read more here.
Keywords: step economy; alkyne annulation; step; activation alkyne ... See more keywords
A Versatile Pd-Catalyzed Alkyne Annulation Process for Benzo[a]carbazoles and their Anticancer Analogues
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DOI: 10.1021/acsomega.2c04755
Abstract: A Pd-catalyzed, simple, and divergent approach for the direct synthesis of benzo[a]carbazoles from internal alkynes and N-tosyl-iodoindoles has been demonstrated. This methodology highlights the influences of reaction media and temperature for the synthesis of either… read more here.
Keywords: alkyne annulation; catalyzed alkyne; benzo carbazoles; versatile catalyzed ... See more keywords
Palladium(ii)-catalyzed vinylic geminal double C-H activation and alkyne annulation reaction: synthesis of pentafulvenes.
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DOI: 10.1039/c9cc09564k
Abstract: The first transition-metal-catalyzed vinylic geminal double C(sp2)-H activation and di-substituted alkyne annulation reaction is reported. This palladium(ii)-catalyzed, amide directed reaction of vinylic compounds with di-substituted alkynes offers an efficient synthetic path to pentafulvenes, which are… read more here.
Keywords: geminal double; reaction; catalyzed vinylic; alkyne annulation ... See more keywords