Electrochemical Oxidative Cleavage of Alkynes to Carboxylic Acids.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.2c04204
Abstract: A sustainable method for converting terminal alkynes into their corresponding carboxylic acids is reported using synthetic electrolysis in an undivided cell at room temperature. This protocol, avoiding transition metal catalysis and stoichiometric chemical oxidants, tolerates… read more here.
Keywords: alkynes carboxylic; carboxylic acids; cleavage alkynes; oxidative cleavage ... See more keywords
Three-component addition of terminal alkynes, carboxylic acids, and tert-butyl hypochlorite.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc00374k
Abstract: This paper described the unprecedented three-component addition of terminal alkynes, carboxylic acids, and tert-butyl hypochlorite. This new type of addition proceeds smoothly to produce gem-dichloroalkane derivatives in satisfactory to excellent yields via successive two-time additions… read more here.
Keywords: addition; component addition; alkynes carboxylic; addition terminal ... See more keywords