A controlled selective synthesis of dihydropyrans through tandem reaction of alkynes with diazo compounds.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc01616f
Abstract: We report here an effective protocol to prepare highly functionalized dihydropyrans via sequential reaction of cross-coupling-intramolecular Michael addition of functionalized terminal alkynes and diazo compounds under mild reaction conditions. Importantly, by choosing different ligands, the… read more here.
Keywords: selective synthesis; diazo compounds; synthesis dihydropyrans; alkynes diazo ... See more keywords
Copper-catalyzed 1,1-arylalkylation of terminal alkynes with diazo esters and organoboronic acids.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc07461a
Abstract: A novel copper-catalyzed 1,1-arylalkylation of terminal alkynes with diazo esters and organoboronic acids is described. With this methodology, (E)-β-aryl-β,γ-unsaturated esters can be easily constructed in good to excellent yields directly from readily available and inexpensive… read more here.
Keywords: arylalkylation terminal; diazo esters; terminal alkynes; alkynes diazo ... See more keywords