Cyclocarbonylation-Iodination of terminal alkynes with ketones and ICl via 1,2-migration
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DOI: 10.1016/j.tetlet.2020.152374
Abstract: Abstract A simple, three-component, one-pot, room-temperature reaction of cyclocarbonylation-iodination is developed from terminal alkynes, ketones, and ICl. The reaction proceeds through the formation of 3°-propargyl alcohols and a subsequent 1,2-shift lead to the formation of… read more here.
Keywords: ketones icl; alkynes ketones; cyclocarbonylation iodination; iodination terminal ... See more keywords
Catalytic One-Pot Synthesis of Trisubstituted Allenes from Terminal Alkynes and Ketones.
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DOI: 10.1021/acs.orglett.7b02443
Abstract: An efficient one-pot synthesis of trisubstituted allenes from readily available terminal alkynes and ketones is realized. A wide range of trisubstituted allenes may be synthesized efficiently via this method. Preliminary mechanistic studies revealed that CuI… read more here.
Keywords: alkynes ketones; one pot; pot synthesis; terminal alkynes ... See more keywords
Iodine-catalyzed synthesis of benzoxazoles using catechols, ammonium acetate, and alkenes/alkynes/ketones via C–C and C–O bond cleavage
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DOI: 10.1039/d2ra03340b
Abstract: An efficient metal-free synthesis strategy of benzoxazoles was developed via coupling catechols, ammonium acetate, and alkenes/alkynes/ketones. The developed methodology represents an operationally simple, one-pot and large-scale procedure for the preparation of benzoxazole derivatives using molecular… read more here.
Keywords: catechols ammonium; synthesis; alkynes ketones; ammonium acetate ... See more keywords