Electrochemical Oxidative Oxydihalogenation of Alkynes for the Synthesis of α,α-Dihaloketones.
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DOI: 10.1021/acs.orglett.0c00052
Abstract: An electrochemical oxydihalogenation of alkynes has been developed for the first time. Using this sustainable protocol, a variety of α,α-dihaloketones can be prepared with readily available CHCl3, CH2Cl2, ClCH2CH2Cl, and CH2Br2 as the halogen source… read more here.
Keywords: oxydihalogenation alkynes; alkynes synthesis; oxidative oxydihalogenation; electrochemical oxidative ... See more keywords
Palladium-catalyzed nucleomethylation of alkynes for synthesis of methylated heteroaromatic compounds
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc03294e
Abstract: Herein, we disclosed a novel and efficient palladium-catalyzed nucleomethylation of alkynes for the simultaneous construction of the heteroaromatic ring and methyl group. The 3-methylindoles, 3-methylbenzofurans and 4-methylisoquinolines were obtained in moderate to excellent yields. Notably,… read more here.
Keywords: catalyzed nucleomethylation; palladium catalyzed; nucleomethylation alkynes; alkynes synthesis ... See more keywords