Stereodivergent synthesis of 2-alkynyl buta-1,3-dienes using Sonogashira coupling with controllable retention or inversion of olefin geometry
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DOI: 10.1016/j.tetlet.2019.151565
Abstract: Abstract A stereodivergent approach to 2-alkynyl buta-1,3-dienes from a single stereoisomer of starting α-bromoenal has been developed. By simply switching the sequence of Sonogashira and Horner-Wadsworth-Emmons reactions, it is possible to obtain these branched dienynes… read more here.
Keywords: alkynyl buta; retention; geometry; buta dienes ... See more keywords