Lewis-Acid-Catalyzed Asymmetric Alkynylation of Alkynyl 1,2-Diketones: Controllable Formation of 3(2H)-Furanones and α-Hydroxy Ketones.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c02505
Abstract: We report the highly regio- and enantioselective alkynylation of alkynyl 1,2-diketones under Lewis acid catalysis, leading to the formation of a series of biologically important 3(2H)-furanones with high to excellent ee values. Moreover, a slight… read more here.
Keywords: hydroxy ketones; lewis acid; alkynylation alkynyl; alkynyl diketones ... See more keywords
Brønsted base-catalyzed annulation of allyl ketones and alkynyl 1,2-diketones.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical communications"
DOI: 10.1039/c8cc01020j
Abstract: The discovery of new reaction modes mediated by easily available substrates is an important research topic in organic synthesis. Allyl ketones and related compounds have been demonstrated to undergo γ- or α-selective additions to different… read more here.
Keywords: ketones alkynyl; allyl; base catalyzed; alkynyl diketones ... See more keywords