Alkynyl triazenes enable divergent syntheses of 2-pyronesâ€
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DOI: 10.1039/d1sc02583j
Abstract: The 2-pyrone motif occurs frequently in bioactive natural products and is appreciated as synthetic intermediates. However, only few methods allow for diversifying functional group modifications on this relevant heterocycle. The distinct properties of 1-alkynyl triazenes… read more here.
Keywords: syntheses pyrones; triazenes enable; enable divergent; group ... See more keywords
Gold-catalyzed synthesis of oxazoles from alkynyl triazenes and dioxazoles
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DOI: 10.1039/d2ra04559a
Abstract: A gold-catalyzed regioselective [3 + 2] cycloaddition of alkynyl triazenes with 1,2,4-dioxazoles was developed. The triazene group in the products could be replaced to obtain iodo-oxazoles, providing potential transformations to diverse oxazole structures. This protocol… read more here.
Keywords: triazenes dioxazoles; oxazoles alkynyl; synthesis oxazoles; alkynyl triazenes ... See more keywords
Chemo- and regio-divergent access to fluorinated 1-alkyl and 1-acyl triazenes from alkynyl triazenes
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DOI: 10.1039/d2sc00294a
Abstract: The 1,1,2,2-tetrafluoroethylene unit is prevalent in bioactive molecules and functional materials. Despite being in principle a straightforward strategy to access this motif, the direct tetrafluorination of alkynes involves very hazardous or inconvenient reagents. Therefore, safer… read more here.
Keywords: fluorinated alkyl; chemo regio; regio divergent; alkynyl triazenes ... See more keywords