Chromium(III)-catalyzed C(sp2)-H Alkynylation, Allylation, and Naphthalenation of Secondary Amides with Trimethylaluminum as Base.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c00127
Abstract: Among base metals used for C-H activation reactions, chromium(III) is rather unexplored despite its natural abundance and low toxicity. We report herein chromium(III)-catalyzed C(sp2)-H functionalization of an ortho-position of aromatic and α,β-unsaturated secondary amides using… read more here.
Keywords: iii; catalyzed sp2; secondary amides; iii catalyzed ... See more keywords
Radical-mediated sulfonyl alkynylation, allylation, and cyanation of propellane.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc02249k
Abstract: Bicyclo[1.1.1]pentane (BCP) is widely applied as the bioisostere for aryl, internal alkynes, and tert-butyl groups in medicinal chemistry. We herein disclose an efficient and practical preparation of sulfonyl alkynyl/allyl/cyano-substituted BCP derivatives through a novel radical-mediated… read more here.
Keywords: alkynylation allylation; allylation cyanation; propellane; radical mediated ... See more keywords