Catalytic C-H alkynylation of benzylamines and aldehydes with aldimine-directing groups generated in situ.
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DOI: 10.1039/d3cc01414b
Abstract: Iridium-catalysed regioselective C-H alkynylation of unprotected primary benzylamines and aliphatic aldehydes has been achieved using in situ-installed aldimine directing groups. This protocol provides a straightforward route for the synthesis of the alkynylated primary benzylamine and… read more here.
Keywords: alkynylation benzylamines; directing groups; catalytic alkynylation; benzylamines aldehydes ... See more keywords