A common genetic variant rs2821557 in KCNA3 is linked to the severity of multiple sclerosis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24596
Abstract: The rate of symptom accumulation distinguishes between slowly and rapidly progressing forms of multiple sclerosis (MS). Given that a patient's genetics can affect the rate of disease progression, identification of genetic variants associated with rapid… read more here.
Keywords: sclerosis; allele carriers; multiple sclerosis; disease progression ... See more keywords
Common polymorphism in the cannabinoid receptor gene type 2 (CB2R) rs3123554 are associated with metabolic changes after two different hypocaloric diets with different dietary fatty profiles.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical nutrition"
DOI: 10.1016/j.clnu.2018.11.013
Abstract: BACKGROUND The role of CB2R gene variants on weight loss after a dietary intervention has been investigated in few studies. OBJECTIVE We evaluate the effect of this genetic variant (rs3123554) of CB2R gene on cardiovascular… read more here.
Keywords: non allele; hypocaloric diets; different hypocaloric; allele carriers ... See more keywords
Effects of polymorphism rs3123554 in the cannabinoid receptor gene type 2 (CB2R) on metabolic and adiposity parameters after weight loss with two hypocaloric diets.
Sign Up to like & getrecommendations! Published in 2018 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2018.02.030
Abstract: BACKGROUND The role of CB2R gene variants on weight loss after a dietary intervention remained unclear. OBJECTIVE Our aim was to analyze the effects of rs3123554 of CB2R receptor gene on metabolic and adiposity parameters… read more here.
Keywords: hypocaloric diets; weight loss; allele carriers; receptor gene ... See more keywords
BDNF Val66Met polymorphism and posttraumatic stress symptoms in U.S. military veterans: Protective effect of physical exercise
Sign Up to like & getrecommendations! Published in 2019 at "Psychoneuroendocrinology"
DOI: 10.1016/j.psyneuen.2018.10.011
Abstract: The Met allele of the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is associated with reduced levels of BDNF release, heightened hypothalamic-pituitary-adrenal axis reactivity, and impaired fear extinction. As a result, Met allele carriers may be… read more here.
Keywords: ptsd symptoms; bdnf val66met; allele carriers; met allele ... See more keywords
Association between cytokine genes polymorphisms and type 1 diabetes: a case-control study on Saudi population
Sign Up to like & getrecommendations! Published in 2018 at "Immunological Investigations"
DOI: 10.1080/08820139.2017.1416398
Abstract: ABSTRACT Background: Association studies of genes encoding cytokines that play an important role in inflammatory response represent one approach to finding type 1 diabetes (T1D) disease genes. The aim of this study was to investigate… read more here.
Keywords: cytokine genes; cytokine; control; type diabetes ... See more keywords
Polymorphism of neuropeptide Y gene rs16147 modifies the response to a hypocaloric diet on cardiovascular risk biomarkers and adipokines
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Human Nutrition and Dietetics"
DOI: 10.1111/jhn.12406
Abstract: BACKGROUND The main genetic variant described in NPY gene is rs16147 (G-399A) and it is located within the promoter region upstream of the gene for neropeptide Y (NPY). We evaluate the effects of the rs16147… read more here.
Keywords: non allele; gene; decrease non; allele carriers ... See more keywords
Dietary Intervention during 9 Months with a Hypocaloric Diet, Interaction of the Genetic Variant of Adiponectin Gene rs822393 with Metabolic Parameters
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/7058389
Abstract: Background and Aims rs822393 (-4522C/T) genetic variant is associated with hypoadiponectinemia and other metabolic parameters. The aim of our investigation was to analyze the effects of a hypocaloric diet with Mediterranean dietary pattern during 9… read more here.
Keywords: genetic variant; adiponectin; cholesterol; allele carriers ... See more keywords
Alcohol-metabolizing Enzymes' Gene Polymorphisms and Susceptibility to Multiple Head and Neck Cancers
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Prevention Research"
DOI: 10.1158/1940-6207.capr-18-0449
Abstract: Multiple primary tumors (MPT), especially in the hypopharynx and esophagus, are challenging in patients with head and neck cancer (HNC). Alcohol and alcohol-metabolizing genes were reported to be related to upper digestive tract cancers. Here,… read more here.
Keywords: upper digestive; allele carriers; metabolizing enzymes; alcohol metabolizing ... See more keywords
Candidate genetic variants and antidepressant-related fall risk in middle-aged and older adults
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DOI: 10.1371/journal.pone.0266590
Abstract: Background Antidepressant use has been associated with increased fall risk. Antidepressant-related adverse drug reactions (e.g. orthostatic hypotension) depend partly on genetic variation. We hypothesized that candidate genetic polymorphisms are associated with fall risk in older… read more here.
Keywords: fall risk; allele carriers; variant allele; risk ... See more keywords
ADORA2A C Allele Carriers Exhibit Ergogenic Responses to Caffeine Supplementation
Sign Up to like & getrecommendations! Published in 2020 at "Nutrients"
DOI: 10.3390/nu12030741
Abstract: Caffeine’s ergogenic effects on exercise performance are generally explained by its ability to bind to adenosine receptors. ADORA2A is the gene that encodes A2A subtypes of adenosine receptors. It has been suggested that ADORA2A gene… read more here.
Keywords: effects caffeine; allele carriers; exercise performance; adora2a allele ... See more keywords