Articles with "allelic conversion" as a keyword



Multistep allelic conversion in mouse pre-implantation embryos by AAV vectors

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Published in 2024 at "Scientific Reports"

DOI: 10.1038/s41598-024-70853-1

Abstract: Site-specific recombinases (SSRs) are critical for achieving precise spatiotemporal control of engineered alleles. These enzymes play a key role in facilitating the deletion or inversion of loci flanked by recombination sites, resulting in the activation… read more here.

Keywords: conversion; aav vectors; allelic conversion; mouse ... See more keywords