Biased allelic expression in tissues of F1 hybrids between tropical and temperate lotus (Nelumbo nuicfera).
Sign Up to like & getrecommendations! Published in 2021 at "Plant molecular biology"
DOI: 10.1007/s11103-021-01138-8
Abstract: KEY MESSAGE The genome-wide allele-specific expression in F1 hybrids from the cross of tropical and temperate lotus unveils how cis-regulatory divergences affect genes in key pathways related to ecotypic divergence. Genetic variation, particularly cis-regulatory variation,… read more here.
Keywords: tropical temperate; temperate lotus; lotus; expression ... See more keywords
A Bayesian mixture model for the analysis of allelic expression in single cells
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-13099-0
Abstract: Allele-specific expression (ASE) at single-cell resolution is a critical tool for understanding the stochastic and dynamic features of gene expression. However, low read coverage and high biological variability present challenges for analyzing ASE. We demonstrate… read more here.
Keywords: mixture model; expression single; expression; allelic expression ... See more keywords
Spatial and temporal regulation of parent-of-origin allelic expression in the endosperm
Sign Up to like & getrecommendations! Published in 2022 at "Plant Physiology"
DOI: 10.1093/plphys/kiac520
Abstract: Genomic imprinting promotes differential expression of parental alleles in the endosperm of flowering plants, and is regulated by epigenetic modification such as DNA methylation and histone tail modifications in chromatin. After fertilization, the endosperm develops… read more here.
Keywords: parent origin; genomic imprinting; expression; allelic expression ... See more keywords
Abstract 862: Multi-omic analysis of allelic expression patterns of imprinted and non-imprinted genes in cancer and their association with drug response
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-862
Abstract: Malignant cells undergo a broad array of epigenetic changes, including changes in imprinting patterns. In normal cells, imprinted genes have parent of origin-specific monoallelic expression, which is controlled via epigenetic mechanisms. Imprinted gene loci are… read more here.
Keywords: cancer; patterns imprinted; allelic expression; expression patterns ... See more keywords
Allelic expression patterns of imprinted and non-imprinted genes in cancer cell lines from multiple histologies
Sign Up to like & getrecommendations! Published in 2025 at "Clinical Epigenetics"
DOI: 10.1186/s13148-025-01883-3
Abstract: Imprinted genes are epigenetically regulated in normal tissues to follow monoallelic expression according to the parent of origin of each allele. Some of these patterns are dysregulated in cancer. We developed a novel computational multi-omic… read more here.
Keywords: cancer; cell lines; allelic expression; imprinted genes ... See more keywords
Mapping the mouse Allelome reveals tissue-specific regulation of allelic expression
Sign Up to like & getrecommendations! Published in 2017 at "eLife"
DOI: 10.7554/elife.25125
Abstract: To determine the dynamics of allelic-specific expression during mouse development, we analyzed RNA-seq data from 23 F1 tissues from different developmental stages, including 19 female tissues allowing X chromosome inactivation (XCI) escapers to also be… read more here.
Keywords: mapping mouse; tissue specific; mouse allelome; expression ... See more keywords