Allelic Polymorphisms of KIRs and HLAs Predict Favorable Responses to Tyrosine Kinase Inhibitors in CML
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DOI: 10.1158/2326-6066.cir-17-0462
Abstract: In CML patients treated with tyrosine kinase inhibitors, KIR alleles were associated with patient outcome. The combination of alleles at KIR3DL1 and HLA-B loci were found to predict the therapeutic effects of tyrosine kinase inhibitor… read more here.
Keywords: kinase inhibitors; allelic polymorphisms; kir hla; kinase ... See more keywords
Comparison of the impact of allelic polymorphisms in PfAMA1 on the induction of T Cell responses in high and low malaria endemic communities in Ghana
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DOI: 10.1186/s12936-021-03900-1
Abstract: Background Malaria eradication requires a combined effort involving all available control tools, and these efforts would be complemented by an effective vaccine. The antigen targets of immune responses may show polymorphisms that can undermine their… read more here.
Keywords: cell responses; allelic polymorphisms; high low; responses high ... See more keywords