Allenoates in Enantioselective [2+2] Cycloadditions: From a Mechanistic Curiosity to a Stereospecific Transformation.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.8b10008
Abstract: Identification of a novel catalyst-allenoate pair allows enantioselective [2+2] cycloaddition of α-methylstyrene. To understand the origin of selectivity, a detailed mechanistic investigation was conducted. Herein, two competing reaction pathways are proposed, which operate simultaneously and… read more here.
Keywords: curiosity stereospecific; curiosity; cycloadditions mechanistic; enantioselective cycloadditions ... See more keywords
Phosphine-catalyzed γ-addition of nitroacetates to allenoates for enantioselective creation of α,α-disubstituted α-amino acid precursors
Sign Up to like & getrecommendations! Published in 2021 at "Organic Chemistry Frontiers"
DOI: 10.1039/d1qo01016f
Abstract: Enantioselective γ-addition of readily available α-substituted nitroacetates to allenoates has been achieved. read more here.
Keywords: phosphine catalyzed; catalyzed addition; addition; addition nitroacetates ... See more keywords