Photoredox/Copper Dual-Catalyzed Regioselective 1,4-Arylcyanation of 1,3-Enynes for Multifunctionalized Allenyl Nitriles.
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DOI: 10.1021/acs.orglett.5c02449
Abstract: A copper/photoredox dual-catalysis-enabled 1,4-arylcyanation of 1,3-enynes to afford tetrasubstituted allenyl nitriles was initially developed. The reaction features good reaction generality and high reaction regioselectivity, providing facile access to multifunctionalized allenyl nitriles. This strategy achieves the… read more here.
Keywords: photoredox copper; multifunctionalized allenyl; allenyl nitriles; arylcyanation enynes ... See more keywords