Update on the use of allergen challenge chambers in immunotherapy: clinical implications.
Sign Up to like & getrecommendations! Published in 2022 at "Current opinion in allergy and clinical immunology"
DOI: 10.1097/aci.0000000000000808
Abstract: PURPOSE OF REVIEW This review aims to reflect on and discuss recent evidence of applicability of allergen exposure chambers (AEC) for allergen immunotherapy studies, especially focussing on validation of AECs, technical documentation and future perspectives.… read more here.
Keywords: use allergen; challenge chambers; update use; allergen ... See more keywords
Lack of Ecto-5′-Nucleotidase Protects Sensitized Mice against Allergen Challenge
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DOI: 10.3390/biom12050697
Abstract: Ecto-5′-nucleotidase (CD73), the ectoenzyme that together with CD39 is responsible for extracellular ATP hydrolysis and adenosine accumulation, regulates immune/inflammatory processes by controlling innate and acquired immunity cell functions. We previously demonstrated that CD73 is required… read more here.
Keywords: allergen challenge; lack ecto; ecto nucleotidase; sensitized mice ... See more keywords
Segmental Bronchial Allergen Challenge Elicits Distinct Metabolic Phenotypes in Allergic Asthma
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DOI: 10.3390/metabo12050381
Abstract: Asthma is a complex syndrome associated with episodic decompensations provoked by aeroallergen exposures. The underlying pathophysiological states driving exacerbations are latent in the resting state and do not adequately inform biomarker-driven therapy. A better understanding… read more here.
Keywords: metabolic phenotypes; allergen challenge; segmental bronchial; bronchial allergen ... See more keywords