Reduced mouse allergen is associated with epigenetic changes in regulatory genes, but not mouse sensitization, in asthmatic children
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Research"
DOI: 10.1016/j.envres.2017.04.025
Abstract: ABSTRACT Chronic exposure to mouse allergen may contribute greatly to the inner‐city asthma burden. We hypothesized that reducing mouse allergen exposure may modulate the immunopathology underlying symptomatic pediatric allergic asthma, and that this occurs through… read more here.
Keywords: mouse allergen; epigenetic regulation; allergen; allergen exposure ... See more keywords
Green propolis increases myeloid suppressor cells and CD4+Foxp3+ cells and reduces Th2 inflammation in the lungs after allergen exposure.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2019.112496
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Propolis is a natural product produced by honeybees used as a medicine at least to 300 BC. In the last decades, several studies showed biological and pharmacological properties of propolis, witch scientifically explains… read more here.
Keywords: cd4 foxp3; th2 inflammation; propolis; allergen exposure ... See more keywords
The links between allergen exposure and sensitization in children and adolescents: an overview for the clinician
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2022.2072297
Abstract: ABSTRACT Introduction The links between allergen exposure and sensitization are complex and depend not only on the type of allergen but on various genetic and environmental factors. Areas covered This review discusses the link between… read more here.
Keywords: allergen exposure; sensitization; exposure sensitization; children adolescents ... See more keywords
Allergen exposure chambers: implementation in clinical trials in allergen immunotherapy
Sign Up to like & getrecommendations! Published in 2020 at "Clinical and Translational Allergy"
DOI: 10.1186/s13601-020-00336-9
Abstract: Allergen exposure chambers (AECs) have been developed for controlled allergen challenges of allergic patients mimicking natural exposure. As such, these facilities have been utilized e.g., for proof of concept, dose finding or the demonstration of… read more here.
Keywords: allergen exposure; allergen immunotherapy; exposure; exposure chambers ... See more keywords
Effects of Controlled Diesel Exhaust and Allergen Exposure on microRNA and Gene Expression in Humans. Modulation of Lung Inflammatory Markers Associated with Asthma
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the American Thoracic Society"
DOI: 10.1513/annalsats.201706-479mg
Abstract: RATIONALE Air pollution may contribute to the development of allergic diseases, including asthma, by enhancing immune responses to allergen, but the effects on microRNA, messenger RNA, and inflammatory markers remain unexplored. OBJECTIVES To determine if… read more here.
Keywords: inflammatory markers; allergen; allergen exposure; diesel exhaust ... See more keywords
TGF-β1 Drives Inflammatory Th Cell But Not Treg Cell Compartment Upon Allergen Exposure
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.763243
Abstract: TGF-β1 is known to have a pro-inflammatory impact by inducing Th9 and Th17 cells, while it also induces anti-inflammatory Treg cells (Tregs). In the context of allergic airway inflammation (AAI) its dual role can be… read more here.
Keywords: allergen; treg; tgf; allergen exposure ... See more keywords