Exopolysaccharide from Lacticaseibacillus rhamnosus induces IgA production in airways and alleviates allergic airway inflammation in mouse model.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202250135
Abstract: The currently observed high prevalence of allergic diseases has been associated with changes in microbial exposure in industrialized countries. Defined bacterial components represent a new strategy for modulating the allergic immune response. We show that… read more here.
Keywords: airway inflammation; allergic airway; lacticaseibacillus rhamnosus; mouse model ... See more keywords
Abscisic acid suppresses the activation of NLRP3 inflammasome and oxidative stress in murine allergic airway inflammation
Sign Up to like & getrecommendations! Published in 2021 at "Phytotherapy Research"
DOI: 10.1002/ptr.7051
Abstract: Abscisic acid (ABA), a well‐known natural phytohormone reportedly exerts anti‐inflammatory and anti‐oxidative properties in diabetes and colitis. However, the efficacy of ABA against allergic airway inflammation and the underlying mechanism remain unknown. Herein, an OVA‐induced… read more here.
Keywords: allergic airway; inflammation; airway inflammation; nlrp3 inflammasome ... See more keywords
T Follicular Helper Cells in Asthma Through Murine Models of Allergic Airway Disease.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1736-6_20
Abstract: The development of allergen-specific IgE is one of the hallmark symptoms of allergic diseases, including asthma. T follicular helper cells (TFH) are a subset of CD4+ T cells that play a critical role in T-dependent… read more here.
Keywords: allergic airway; airway disease; helper cells; follicular helper ... See more keywords
OVA-Induced Allergic Airway Inflammation Mouse Model.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8994-2_28
Abstract: Asthma is a worldwide public health issue, affecting the sufferer's quality of life. Many researchers are extensively studying the cellular processes involved in the affected airways. Experimental asthma using animals has been performed for a… read more here.
Keywords: allergic airway; inflammation; airway inflammation; induced allergic ... See more keywords
ACE2 expression in allergic airway disease may decrease the risk and severity of COVID-19
Sign Up to like & getrecommendations! Published in 2020 at "European Archives of Oto-rhino-laryngology"
DOI: 10.1007/s00405-020-06408-7
Abstract: The coronavirus disease (COVID-19) is caused by Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and presents with respiratory symptoms which can be life threatening in severe cases. At the start of the pandemic, allergy, asthma, and… read more here.
Keywords: expression; risk; severity covid; disease ... See more keywords
Innate immunity as the orchestrator of allergic airway inflammation and resolution in asthma.
Sign Up to like & getrecommendations! Published in 2017 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2017.04.027
Abstract: The respiratory system is constantly in direct contact with the environment and, has therefore, developed strong innate and adaptive immune responses to combat pathogens. Unlike adaptive immunity which is mounted later in the course of… read more here.
Keywords: innate; allergic airway; immunity; airway inflammation ... See more keywords
Shikonin alleviates allergic airway remodeling by inhibiting the ERK‐NF‐&kgr;B signaling pathway
Sign Up to like & getrecommendations! Published in 2017 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2017.05.011
Abstract: Abstract Shikonin is a naphthoquinone extracted from the root of Lithospermum erythrorhizon, and has been reported to suppress allergic airway inflammation in mice. However, the underlying mechanisms are unclear and need to be further elucidated.… read more here.
Keywords: allergic airway; alleviates allergic; shikonin alleviates; shikonin ... See more keywords
Pinocembrin attenuates allergic airway inflammation via inhibition of NF‐&kgr;B pathway in mice
Sign Up to like & getrecommendations! Published in 2017 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2017.10.005
Abstract: Abstract Pinocembrin, one of the primary flavonoids in propolis, possesses many biological activities, including anti‐inflammation, anti‐oxidation and immunoregulation. This study aimed to evaluate whether pinocembrin could attenuate ovalbumin (OVA)‐induced allergic airway inflammation in mice and… read more here.
Keywords: pinocembrin; allergic airway; inhibition; inflammation ... See more keywords
Aloperine suppresses allergic airway inflammation through NF‐&kgr;B, MAPK, and Nrf2/HO‐1 signaling pathways in mice
Sign Up to like & getrecommendations! Published in 2018 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2018.11.003
Abstract: &NA; To explore the effects of aloperine (ALO) on allergic airway inflammation, we investigated whether its mechanism is related with NF‐&kgr;B, MAPK, and Nrf2/HO‐1 signaling pathways. Histochemical staining and inflammatory cell count were used to… read more here.
Keywords: allergic airway; signaling pathways; kgr mapk; airway inflammation ... See more keywords
Dexamethasone alleviate allergic airway inflammation in mice by inhibiting the activation of NLRP3 inflammasome.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.106017
Abstract: Dexamethasone (DEX) is the mainstay treatment for asthma, which is a common chronic airway inflammation disease. However, the mechanism of DEX resolute symptoms of asthma is not completely clear. Here, we aimed to analyze the… read more here.
Keywords: allergic airway; dex; airway inflammation; mice ... See more keywords
Melatonin biosynthesis restored by CpG oligodeoxynucleotides attenuates allergic airway inflammation via regulating NLRP3 inflammasome.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.117067
Abstract: AIMS Both CpG oligodeoxynucleotide (CpG-ODN) and melatonin have been reported to induce Th1 response and contribute to allergic asthma resistance. Here, we aimed to reveal how they confer such effect as well as whether they… read more here.
Keywords: cpg odn; allergic airway; inflammation; airway inflammation ... See more keywords