Immunoregulatory effects of Lactococcus lactis‐derived extracellular vesicles in allergic asthma
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12138
Abstract: Abstract Background Probiotics have been shown to prevent various allergic diseases by producing extracellular vesicles (EVs). However, the role of EVs in allergic asthma has not yet been completely determined. Methods Gut microbial composition, mainly… read more here.
Keywords: extracellular vesicles; allergic asthma; lactis; mice ... See more keywords
Identification of surrogate prognostic biomarkers for allergic asthma in nasal epithelial brushing samples by WGCNA
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27790
Abstract: Allergic asthma is a lower respiratory tract disease of Th2 inflammation with multiple molecular mechanisms. The upper and lower airways can be unified by the concept of a united airway and, as such, gene expression… read more here.
Keywords: prognostic biomarkers; surrogate; identification surrogate; biomarkers allergic ... See more keywords
Cholinergic anti‐inflammatory pathway confers airway protection against oxidative damage and attenuates inflammation in an allergic asthma model
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29101
Abstract: Asthma is characterized by the influx of inflammatory cells, especially of eosinophils as well as reactive oxygen species (ROS) production, driven by the release of the T helper 2 (Th2)‐cell‐associated cytokines. The cholinergic anti‐inflammatory pathway… read more here.
Keywords: anti inflammatory; inflammation; inflammation allergic; inflammatory pathway ... See more keywords
Both living and dead Faecalibacterium prausnitzii alleviate HDM-induced allergic asthma through the modulation of gut microbiota and short-chain fatty acid (SCFAs) production.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.11207
Abstract: BACKGROUND Asthma is increasingly prevalent worldwide, and novel strategies to prevent or treat this disease are needed. Probiotic intervention has recently been reported to be effective for asthma prevention. Here, we explored the effects of… read more here.
Keywords: living dead; hdm induced; scfas production; prausnitzii ... See more keywords
Murine Models of Allergic Asthma.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6786-5_10
Abstract: Allergic asthma is a heterogeneous inflammatory lung disease affecting millions of people worldwide and with a steadily increasing incidence. Mouse models have been of utmost importance in uncovering key inflammatory cell types, cytokines, and pathways… read more here.
Keywords: murine models; inflammatory; biology; asthma ... See more keywords
Subcutaneous and Sublingual Immunotherapy in a Mouse Model of Allergic Asthma.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6786-5_11
Abstract: Allergic asthma, caused by inhaled allergens such as house dust mite or grass pollen, is characterized by reversible airway obstruction, associated with an eosinophilic inflammation of the airways, as well as airway hyper responsiveness and… read more here.
Keywords: immunotherapy; model; ait; mouse model ... See more keywords
Interference of miR-943-3p with secreted frizzled-related proteins4 (SFRP4) in an asthma mouse model
Sign Up to like & getrecommendations! Published in 2019 at "Cell and Tissue Research"
DOI: 10.1007/s00441-019-03026-6
Abstract: The aim of this study is to investigate the potential roles of miR-943-3p and its target gene secreted frizzled-related proteins4 (SFRP4) in allergic asthma and elucidate its underlying mechanism, which may prompt a new clue… read more here.
Keywords: frizzled related; mir 943; sfrp4; asthma ... See more keywords
Airway inflammation induces anxiety-like behavior through neuroinflammatory, neurochemical, and neurometabolic changes in an allergic asthma model.
Sign Up to like & getrecommendations! Published in 2022 at "Metabolic brain disease"
DOI: 10.1007/s11011-022-00907-8
Abstract: Allergic asthma is characterized by chronic airway inflammation and is constantly associated with anxiety disorder. Recent studies showed bidirectional interaction between the brain and the lung tissue. However, where and how the brain is affected in… read more here.
Keywords: airway inflammation; like behavior; allergic asthma; anxiety like ... See more keywords
Alveolar Macrophages in Allergic Asthma: the Forgotten Cell Awakes
Sign Up to like & getrecommendations! Published in 2017 at "Current Allergy and Asthma Reports"
DOI: 10.1007/s11882-017-0681-6
Abstract: Purpose of ReviewThe role of alveolar macrophages in innate immune responses has long been appreciated. Here, we review recent studies evaluating the participation of these cells in allergic inflammation.Recent FindingsImmediately after allergen exposure, monocytes are… read more here.
Keywords: asthma forgotten; alveolar macrophages; forgotten cell; inflammation ... See more keywords
Allergic asthma aggravated atherosclerosis increases cholesterol biosynthesis and foam cell formation in apolipoprotein E-deficient mice.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.09.085
Abstract: Several studies have demonstrated that allergic asthma can induce atherosclerosis formation in mice. Moreover, allergic asthma and atherosclerosis have been shown to be strongly associated with dyslipidemia. In this study, we investigated the underlying mechanism… read more here.
Keywords: foam cell; formation; cholesterol biosynthesis; mice ... See more keywords
Role of neutrophils in allergic asthma.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2018.05.006
Abstract: The contribution of neutrophils to asthma pathogenesis has been mainly studied in the context of non-allergic neutrophilic asthma. However, neutrophils can also be rapidly recruited and are largely present in the airways of allergic eosinophilic… read more here.
Keywords: neutrophils allergic; role neutrophils; biology; allergic asthma ... See more keywords