Safety and efficacy of a novel 0.5% epinastine topical eyelid cream in allergic conjunctivitis: a phase 3 trial
Sign Up to like & getrecommendations! Published in 2024 at "Japanese Journal of Ophthalmology"
DOI: 10.1007/s10384-024-01108-9
Abstract: The high prevalence of allergic conjunctivitis in Japan necessitates novel, easy-to-use treatment options for prophylactic use. We evaluated the safety and efficacy of a newly-developed 0.5% epinastine topical eyelid cream to prevent the development of… read more here.
Keywords: eyelid cream; topical eyelid; epinastine topical; cream ... See more keywords
Clinically Relevant Activity of the Novel RASP Inhibitor Reproxalap in Allergic Conjunctivitis: The Phase 3 ALLEVIATE Trial.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of ophthalmology"
DOI: 10.1016/j.ajo.2021.04.023
Abstract: PURPOSE To assess the post-acute activity and clinical utility of reproxalap, a novel reactive aldehyde species (RASP) inhibitor, versus vehicle in patients with seasonal allergic conjunctivitis. DESIGN Parallel-group, double-masked, randomized Phase 3 trial. METHODS Two… read more here.
Keywords: phase; conjunctivitis; ocular itching; allergic conjunctivitis ... See more keywords
Novel oleyl amine-modified polymannuronic acid micelle loading tacrolimus for therapy of allergic conjunctivitis.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.06.064
Abstract: Marine polysaccharide-based nanomaterial attracted considerable attention due to its biocompatibility and biodegradability. Here, a novel polymannuronic acid derivative (PM-C18) was synthesized as nanocarrier modified with hydrophobic oleyl amine. Its structure was confirmed by Fourier-transformed infrared… read more here.
Keywords: polymannuronic acid; allergic conjunctivitis; fk506 loaded; oleyl amine ... See more keywords
PM2.5 Stimulates Macrophage-Derived Thymic Stromal Lymphopoietin (TSLP) to Induce a Mouse Model of Allergic Conjunctivitis
Sign Up to like & getrecommendations! Published in 2025 at "Current Eye Research"
DOI: 10.1080/02713683.2025.2487066
Abstract: Abstract Purpose Increasing epidemiologic evidence has indicated that PM2.5 exposure is strongly correlated with the prevalence of allergic conjunctivitis (AC), but there is no experimental model for elucidating the underlying mechanism involved. We established a… read more here.
Keywords: pm2; mouse model; pm2 exposure; allergic conjunctivitis ... See more keywords
Efficacy and Tolerability of Ketotifen in the Treatment Of Seasonal Allergic Conjunctivitis: Comparison between Ketotifen 0.025% and 0.05% Eye Drops
Sign Up to like & getrecommendations! Published in 2018 at "Ocular Immunology and Inflammation"
DOI: 10.1080/09273948.2018.1530363
Abstract: ABSTRACT Purpose: To study the tolerability and efficacy of two formulations of topical ketotifen ophthalmic solutions for the treatment of seasonal allergic conjunctivitis (SAC). Methods: 81 active SAC patients were treated with either ketotifen 0.025%… read more here.
Keywords: seasonal allergic; ketotifen 025; 025 eye; treatment seasonal ... See more keywords
Effects of Antihistamine-Releasing Contact Lenses on Severe Allergic Conjunctivitis.
Sign Up to like & getrecommendations! Published in 2022 at "Ocular immunology and inflammation"
DOI: 10.1080/09273948.2022.2103001
Abstract: Half of the patients who used CL daily did not wish to switch to spectacles even with ocular-allergic symptoms and findings. Therefore, continued CL use with suppressed ocular allergy can improve productivity and quality of… read more here.
Keywords: allergic conjunctivitis; effects antihistamine; ocular allergic; releasing contact ... See more keywords
Sensitization to Aeroallergens in a Mexican Cohort with Allergic Conjunctivitis: A Cross-sectional Retrospective Study Conducted in Ángeles Puebla Hospital.
Sign Up to like & getrecommendations! Published in 2022 at "Ocular immunology and inflammation"
DOI: 10.1080/09273948.2022.2145487
Abstract: This study aims to evaluate the sensitization distribution of aeroallergens in patients with allergic conjunctivitis (AC) living in a temperate subhumid region and to describe the prevalence in a Mexican cohort. A total of 761… read more here.
Keywords: allergic conjunctivitis; sensitization; cohort; mexican cohort ... See more keywords
Neurotrophic factors and nerve growth factor in ocular allergy.
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Allergy and Clinical Immunology"
DOI: 10.1097/aci.0000000000000555
Abstract: PURPOSE OF REVIEW During allergic reaction, nervous and immune systems mutually interact through release of mediators, including neurotrophic factors and nerve growth factor (NGF). These mediators modulate allergic reaction through binding their receptors expressed by… read more here.
Keywords: allergic conjunctivitis; neurotrophic factors; growth factor; factors nerve ... See more keywords
The roles of omega-3 fatty acids and resolvins in allergic conjunctivitis.
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Allergy and Clinical Immunology"
DOI: 10.1097/aci.0000000000000561
Abstract: PURPOSE OF REVIEW Lipids are one of the most important constituents in our body. Advances of lipidomics are elucidating the new roles of various lipid molecules in allergic diseases. For example, some reports showed anti-inflammatory… read more here.
Keywords: allergic conjunctivitis; omega fatty; lipid mediators; fatty acids ... See more keywords
Neuropathic pain and itch: mechanisms in allergic conjunctivitis
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Allergy and Clinical Immunology"
DOI: 10.1097/aci.0000000000000843
Abstract: Purpose of review Allergic conjunctivitis is highly prevalent and affects up to one third of the general population. The current understanding of the pathophysiology and therapeutic strategies center around the type 2 inflammatory pathway. However,… read more here.
Keywords: itch pain; itch; pain itch; allergic conjunctivitis ... See more keywords
Oral Immunotherapy for Allergic Conjunctivitis Using Transgenic Rice Expressing Hypoallergenic Antigens
Sign Up to like & getrecommendations! Published in 2018 at "Cornea"
DOI: 10.1097/ico.0000000000001758
Abstract: Abstract: Pollinosis, or allergic conjunctivitis and rhinitis induced by pollen, is one of the most common diseases worldwide. In Japan, Japanese cedar (Cryptomeria japonica) pollinosis is a predominant allergic condition that affects more than one-third… read more here.
Keywords: immunotherapy; transgenic rice; conjunctivitis; allergic conjunctivitis ... See more keywords