Bidirectional sensory neuron-immune interactions: a new vision in the understanding of allergic inflammation.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2021.03.012
Abstract: Peripheral neurons (including sensory neurons) are ubiquitously distributed in all tissues, particularly at the interface with the environment. The primary function of sensory neurons is the transmission of sensations of temperature, pain and itch to… read more here.
Keywords: sensory neuron; allergic inflammation; inflammation; sensory neurons ... See more keywords
Environmental allergens induce allergic inflammation through proteolytic maturation of IL-33
Sign Up to like & getrecommendations! Published in 2018 at "Nature Immunology"
DOI: 10.1038/s41590-018-0067-5
Abstract: Allergic inflammation has crucial roles in allergic diseases such as asthma. It is therefore important to understand why and how the immune system responds to allergens. Here we found that full-length interleukin 33 (IL-33FL), an… read more here.
Keywords: allergens induce; allergic inflammation; inflammation; induce allergic ... See more keywords
PGI2 restricts trained ILC2 responses in allergic inflammation.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of immunology"
DOI: 10.1093/jimmun/vkaf088
Abstract: Pulmonary type 2 innate lymphoid cells (ILC2s) exhibit immune memory, termed "trained immunity," which enhances their activation following exposure to an independent protease-containing allergen. The role of prostaglandin I2 (PGI2), a cyclooxygenase (COX) pathway metabolite,… read more here.
Keywords: mice; ilc2 responses; trained ilc2; responses allergic ... See more keywords
Eosinophil-Airway Epithelial Cells crosstalk reveals the eosinophils-mediated DUOX1 up-regulation in a murine allergic inflammation setting.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of leukocyte biology"
DOI: 10.1093/jleuko/qiae232
Abstract: Blood and airway eosinophilia represent markers for the endotype-driven treatment of allergic asthma. Little is known on mechanisms that link eosinophils and airway epithelial cells before and after these cells are infiltrated by eosinophils during… read more here.
Keywords: airway epithelial; hdm; regulation; allergic inflammation ... See more keywords
Regulation of allergic inflammation by dendritic cells.
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Allergy and Clinical Immunology"
DOI: 10.1097/aci.0000000000000603
Abstract: PURPOSE OF REVIEW Dendritic cells are critical in directing inflammatory versus tolerogenic responses. As the burden of allergic disease rises worldwide, increased understanding of mechanisms underlying these diseases is needed. This review highlights research demonstrating… read more here.
Keywords: allergic inflammation; dendritic cell; dendritic cells; allergic disease ... See more keywords
CD300a Regulates Mouse Macrophage Functionality in Allergic Inflammation.
Sign Up to like & getrecommendations! Published in 2023 at "International archives of allergy and immunology"
DOI: 10.1159/000529606
Abstract: BACKGROUND CD300a is an inhibitory receptor (IR) expressed on several leukocytes, including mast cells (MCs) and macrophages (MΦ), important cells in allergic inflammation (AI). We have previously characterized CD300a role on MCs and in vivo… read more here.
Keywords: cd300a; absence; allergic inflammation; resolution ... See more keywords
Fungal-mediated lung allergic airway disease: The critical role of macrophages and dendritic cells
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010608
Abstract: Fungi are abundant in the environment, causing our lungs to be constantly exposed to a diverse range of species. While the majority of these are cleared effectively in healthy individuals, constant exposure to spores (especially… read more here.
Keywords: macrophages dendritic; role; lung; allergic inflammation ... See more keywords
Soluble CD93 in Serum as a Marker of Allergic Inflammation
Sign Up to like & getrecommendations! Published in 2017 at "Yonsei Medical Journal"
DOI: 10.3349/ymj.2017.58.3.598
Abstract: Purpose CD93 is receiving renewed attention as a biomarker of inflammation. We aimed to evaluate the potential for serum sCD93 to serve as a novel biomarker for allergic inflammation. Materials and Methods We enrolled 348… read more here.
Keywords: serum scd93; scd93 levels; allergic inflammation; serum ... See more keywords
Crude Turmeric Extract Improves the Suppressive Effects of Lactobacillus rhamnosus GG on Allergic Inflammation in a Murine Model of House Dust Mite-Induced Asthma
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.01092
Abstract: There is a strong correlation between dysregulation of the gastrointestinal microbiota and development of allergic diseases. The most prevalent therapies for relieving asthma symptoms are associated with serious side effects, and therefore novel approaches are… read more here.
Keywords: house dust; lactobacillus rhamnosus; dust mite; allergic inflammation ... See more keywords
MiR-154-5p-MCP1 Axis Regulates Allergic Inflammation by Mediating Cellular Interactions
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.663726
Abstract: In a previous study, we have demonstrated that p62, a selective receptor of autophagy, can regulate allergic inflammation. In the present study, microRNA array analysis showed that miR-154-5p was increased by antigen (DNP-HSA) in a… read more here.
Keywords: mir 154; allergic inflammation; cellular interactions; mcp1 ... See more keywords
Current Strategies to Modulate Regulatory T Cell Activity in Allergic Inflammation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.912529
Abstract: Over the past decades, atopic diseases, including allergic rhinitis, asthma, atopic dermatitis, and food allergy, increased strongly worldwide, reaching up to 50% in industrialized countries. These diseases are characterized by a dominating type 2 immune… read more here.
Keywords: current strategies; treg cells; allergic inflammation; activity ... See more keywords