Tetrandrine alleviates inflammation and neuron apoptosis in experimental traumatic brain injury by regulating the IRE1α/JNK/CHOP signal pathway
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2786
Abstract: The aim of this study was to investigate the therapeutic roles of Tetrandrine (TET) on traumatic brain injury (TBI) and the underlying mechanism. read more here.
Keywords: traumatic brain; tetrandrine alleviates; brain; brain injury ... See more keywords
CLICs Inhibitor IAA94 Alleviates Inflammation and Injury in Septic Liver by Preventing Pyroptosis in Macrophages.
Sign Up to like & getrecommendations! Published in 2025 at "Inflammation"
DOI: 10.1007/s10753-025-02304-6
Abstract: Macrophage pyroptosis represents a pivotal mechanism underlying acute liver injury during sepsis. Chloride intracellular channel proteins (CLICs) have been linked to inflammatory reflexes, with IAA94 serving as an inhibitor of channel formation characteristic of CLICs.… read more here.
Keywords: pyroptosis; alleviates inflammation; iaa94 alleviates; injury ... See more keywords
PROTAC for Bruton’s tyrosine kinase degradation alleviates inflammation in autoimmune diseases
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DOI: 10.1038/s41421-024-00711-x
Abstract: DMSO/Ibrutinib/L18I (100 nM) treatment and various stimuli processing time patterns read more here.
Keywords: degradation alleviates; alleviates inflammation; tyrosine kinase; kinase degradation ... See more keywords
Lidocaine alleviates inflammation and pruritus in atopic dermatitis by blocking different population of sensory neurons
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Pharmacology"
DOI: 10.1111/bph.16012
Abstract: Atopic dermatitis is a common chronic pruritic inflammatory disease of the skin involving neuro‐immune communication. Neuronal mechanism‐based therapeutic treatments remain lacking. We investigated the efficacy of intravenous lidocaine therapy on atopic dermatitis and the underlying… read more here.
Keywords: lidocaine alleviates; inflammation pruritus; atopic; atopic dermatitis ... See more keywords
Knockdown of TRIM22 regulates the expression of NF-κB/NLRP3 and alleviates inflammation and renal injury in mice with lupus nephritis.
Sign Up to like & getrecommendations! Published in 2025 at "Allergologia et immunopathologia"
DOI: 10.15586/aei.v53i3.1313
Abstract: Lupus nephritis (LN) is a common and clinically challenging complication of the systemic lupus erythematosus (SLE), but effective treatments remain imperative. Tripartite Motif Containing 22 (TRIM22) is a protein involved in various cellular processes, such… read more here.
Keywords: lupus; mice; alleviates inflammation; lupus nephritis ... See more keywords
Pentamidine Alleviates Inflammation and Lipopolysaccharide-Induced Sepsis by Inhibiting TLR4 Activation via Targeting MD2
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.835081
Abstract: Toll-like receptor 4 (TLR4) is a pattern-recognition receptor (PRR) that can recognize lipopolysaccharides (LPS) and initiate the immune response, to protect the body from infection. However, excessive activation of TLR4 induced by LPS leads to… read more here.
Keywords: tlr4; sepsis; activation; pentamidine ... See more keywords
Supplemental 25-hydroxycholecalciferol Alleviates Inflammation and Cardiac Fibrosis in Hens
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DOI: 10.3390/ijms21218379
Abstract: Broiler breeder hens with efficient feed conversion rate under restricted feed intake (R-hens) or allowed unlimited access to feed (Ad-hens) progressed with cardiac functional failure and suffered early sudden death. A supplement of 69 μg… read more here.
Keywords: supplemental hydroxycholecalciferol; cardiac fibrosis; hydroxycholecalciferol; alleviates inflammation ... See more keywords