Dexmedetomidine Alleviates Remifentanil-Induced Hyperalgesia in Rats by Modulating the P2 X 4/BDNF Pathway
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DOI: 10.1007/s11064-025-04377-z
Abstract: In the clinical settings, patients often develop opioid-induced hyperalgesia (OIH) after utilization of high dose intra-operative remifentanil. It is widely considered that systemic α2 agonists, including dexmedetomidine (DEX), have the potential to mitigate postoperative pain… read more here.
Keywords: induced hyperalgesia; alleviates remifentanil; dex; dexmedetomidine alleviates ... See more keywords