PTSD in women is associated with a block in conversion of progesterone to the GABAergic neurosteroids allopregnanolone and pregnanolone measured in plasma
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DOI: 10.1016/j.psyneuen.2018.04.024
Abstract: There is a need to identify new and more effective treatments for posttraumatic stress disorder (PTSD). Allopregnanolone and its stereoisomer pregnanolone (together termed ALLO) are metabolites of progesterone that positively and allosterically modulate GABA effects… read more here.
Keywords: plasma; allo dhp; women ptsd; ratio allo ... See more keywords