High prognostic value of pre-allogeneic stem cell transplantation minimal residual disease detection by WT1 gene expression in AML transplanted in cytologic complete remission.
Sign Up to like & getrecommendations! Published in 2017 at "Leukemia research"
DOI: 10.1016/j.leukres.2017.10.010
Abstract: We analyzed the outcome of allogeneic stem cell transplantation (allo-SCT) in acute myeloid leukemia (AML) patients according to molecular Minimal Residual Disease (MRD) status prior to allo-SCT. MRD was assessed by the quantitative expression of… read more here.
Keywords: allo sct; pre; expression; sct ... See more keywords
Impact of pretransplant leukemic blast% in bone marrow and peripheral blood on transplantation outcomes of patients with acute myeloid leukemia undergoing allogeneic stem cell transplantation in non-CR
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DOI: 10.1038/s41409-017-0028-x
Abstract: The long-term survival rate of patients who underwent allogeneic SCT (allo-SCT) with a non-CR status was as poor as 10–30% [1–3]; however, a more appropriate indicator of the leukemic burden is needed to assess the… read more here.
Keywords: allo sct; patients acute; transplantation; sct ... See more keywords
EBMT prospective observational study on allogeneic hematopoietic stem cell transplantation in T-prolymphocytic leukemia (T-PLL)
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DOI: 10.1038/s41409-019-0448-x
Abstract: Preliminary data suggest that allogeneic stem cell transplantation (allo-SCT) may be effective in T-prolymphocytic leukemia (T-PLL). The purpose of the present observational study was to assess the outcome of allo-SCT in patients aged 65 years… read more here.
Keywords: allo sct; cell transplantation; study; stem cell ... See more keywords
Salvage therapy with dose-escalating ruxolitinib as a bridge to allogeneic stem cell transplantation for refractory hemophagocytic lymphohistiocytosis
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DOI: 10.1038/s41409-019-0577-2
Abstract: Hemophagocytic lymphohistiocytosis (HLH) is a severe, life-threatening immune-dysregulatory disorder manifested as fever, splenomegaly, and cytopenia. HLH is often refractory to standard treatments and poses a significant risk of death, and therefore, it is of great… read more here.
Keywords: ruxolitinib; allo sct; transplantation; salvage ... See more keywords
No difference in survival after HLA mismatched versus HLA matched allogeneic stem cell transplantation in Ewing sarcoma patients with advanced disease
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DOI: 10.1038/s41409-020-01200-x
Abstract: Patients with advanced Ewing sarcoma (AES) carry a poor prognosis. Retrospectively, we analyzed 66 AES patients treated with allogeneic stem cell transplantation (allo-SCT) receiving HLA-mismatched (group A, n = 39) versus HLA-matched grafts (group B, n = 27). Median… read more here.
Keywords: group versus; allo sct; hla mismatched; group ... See more keywords
Impact of telomere length on the outcome of allogeneic stem cell transplantation for poor‐risk chronic lymphocytic leukaemia: results from the GCLLSG CLL3X trial
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Haematology"
DOI: 10.1111/bjh.14219
Abstract: Chronic lymphocytic leukaemia (CLL) is the most common malignancy of the B cell system, affecting predominantly the elderly, with a median diagnostic age around 72 years (Rai, 2015). CLL has a very heterogeneous clinical course… read more here.
Keywords: poor risk; cll; risk; allo sct ... See more keywords
Outcome of relapse after allogeneic HSCT in children with ALL enrolled in the ALL‐SCT 2003/2007 trial
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Haematology"
DOI: 10.1111/bjh.14965
Abstract: Relapse remains the major cause of treatment failure in children with high‐risk acute lymphoblastic leukaemia (ALL) undergoing allogeneic haematopoietic stem‐cell transplantation (allo‐SCT). Prognosis is considered dismal but data on risk factors and outcome are lacking… read more here.
Keywords: outcome; allo sct; relapse; sct ... See more keywords
Enteric‐coated mycophenolate sodium: a new option for GHVD prophylaxis?
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DOI: 10.1111/ejh.12739
Abstract: Acute graft-versus host disease (aGVHD) is a multi-step process occurring after allogeneic hematopoietic stem cell transplantation (allo-SCT), characterized by (I) tissue damage to the recipient by pretransplant preparative chemotherapy, (II) donor T cell activation in… read more here.
Keywords: mycophenolate sodium; allo sct; new option; enteric coated ... See more keywords
Reassessment of clinical implication of pretransplant surgical procedures for pulmonary invasive fungal lesions
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DOI: 10.1111/tid.13023
Abstract: Dealing with the recent series of allogeneic hematopoietic stem cell transplantation (allo‐SCT) performed this decade, we reassessed the clinical impact of pretransplant surgical procedures (SP) for pulmonary lesions of invasive fungal disease (IFD) on subsequent… read more here.
Keywords: pretransplant surgical; procedures pulmonary; allo sct; invasive fungal ... See more keywords
IMPACT OF PRE TRANSPLANT SALVAGE THERAPIES ON OUTCOME OF HODGKIN LYMPHOMA PATIENTS PERFORMING ALLOGENEIC TRANSPLANT.
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DOI: 10.1159/000525819
Abstract: BACKGROUND Allogeneic transplant is an effective salvage therapy in patients with Hodgkin lymphoma (HL) relapsed or refractory to previous treatments. In recent years, immunotherapies (conjugated antibody and checkpoint inhibitors) showed interesting results and were used… read more here.
Keywords: salvage; hodgkin lymphoma; therapies outcome; allo sct ... See more keywords
Thrombopoietin Receptor Agonists for Severe Thrombocytopenia after Allogeneic Stem Cell Transplantation: Experience of a Multicenter Study from the Grupo Español De Trasplante Hematopoyético (GETH)
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-200
Abstract: Introduction Thrombocytopenia is a common complication after allogeneic hematopoietic stem cell transplantation (allo-SCT). Underlying mechanisms are poorly known and usually multifactorial. Its treatment is not well defined, mostly based in platelet transfusion. Thus, is important… read more here.
Keywords: thrombocytopenia; allo sct; study; cell ... See more keywords