Synthesis and Antiproliferative Properties of Bifunctional Allocolchicine Derivatives
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DOI: 10.1055/s-0037-1610146
Abstract: Based on the natural antimitotic agent colchifoline as a lead structure, a series of novel bifunctional allocolchicine congeners were synthesized from commercial colchicine. The new derivatives maintain good cytotoxicity against T3M4, MiaPaCa-2, and PANC-1 cell… read more here.
Keywords: properties bifunctional; bifunctional allocolchicine; antiproliferative properties; synthesis antiproliferative ... See more keywords