Survival Trends in Infants Undergoing Allogeneic Hematopoietic Cell Transplant
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DOI: 10.1001/jamapediatrics.2019.0081
Abstract: Importance Studies demonstrating improved survival after allogeneic hematopoietic cell transplant generally exclude infants. Objective To analyze overall survival trends and other outcomes among infants who undergo allogeneic hematopoietic cell transplant. Design, Setting, and Participants In… read more here.
Keywords: allogeneic hematopoietic; transplant; hematopoietic cell; survival ... See more keywords
Early‐onset severe infections in allogeneic hematopoietic stem cell transplantation recipients with graft failure
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DOI: 10.1002/ajh.25406
Abstract: REFERENCES 1. Srour SA, Devesa SS, Morton LM, et al. Incidence and patient survival of myeloproliferative neoplasms and myelodysplastic/myeloproliferative neoplasms in the United States, 2001-12. Br J Haematol. 2016;174: 382-396. 2. Roaldsnes C, Holst R,… read more here.
Keywords: early onset; onset severe; severe infections; allogeneic hematopoietic ... See more keywords
Age barriers in allogeneic hematopoietic cell transplantation: Raising the silver curtain
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DOI: 10.1002/ajh.27228
Abstract: Allogeneic hematopoietic cell transplantation (HCT) is no longer exclusively for the young. With an aging population, development of non‐intensive remission‐inducing strategies for hematologic malignancies, and novel graft‐versus‐host disease‐prevention platforms, an older population of patients is… read more here.
Keywords: allogeneic hematopoietic; hct; cell transplantation; hematopoietic cell ... See more keywords
Methotrexate Versus Mycophenolate Mofetil Prophylaxis in Allogeneic Hematopoietic Cell Transplantation for Chronic Myeloid Malignancies: A Retrospective Analysis on Behalf of the Chronic Malignancies Working Party of the EBMT
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DOI: 10.1002/ajh.27531
Abstract: Prophylaxis strategies for Graft versus host disease (GVHD) in allogeneic hematopoietic cell transplantation (allo‐HCT) frequently encompass a combination of a calcineurin inhibitor (CNI) with either methotrexate (MTX) or mycophenolate mofetil (MMF). The aim of this… read more here.
Keywords: mtx; cell transplantation; hematopoietic cell; prophylaxis ... See more keywords
Efficacy and Safety of Hetrombopag Versus Thrombopoietin in Promoting Platelet Engraftment After Allogeneic Hematopoietic Stem Cell Transplantation: A Prospective, Multicenter, Randomized Controlled Clinical Trial
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DOI: 10.1002/ajh.27746
Abstract: Allogeneic hematopoietic stem cell transplantation (allo‐HSCT) is pivotal for hematological malignancies but faces challenges in delayed platelet engraftment, poor graft function (PGF), and bleeding risks. Hetrombopag, a thrombopoietin receptor agonist, was evaluated to enhance platelet… read more here.
Keywords: hetrombopag; platelet engraftment; hematopoietic stem; platelet ... See more keywords
Peripheral blood kinetics following total body irradiation and allogeneic hematopoietic stem cell transplantation: Timing matters
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DOI: 10.1002/cam4.5452
Abstract: Total body irradiation (TBI) remains an important component in many conditioning regimens before allogeneic hematopoietic stem cell transplantation (allo‐HSCT). Because of its frequent toxicity, patient selection is crucial, making it of interest to identify factors… read more here.
Keywords: allogeneic hematopoietic; stem cell; cell transplantation; hematopoietic stem ... See more keywords
FLT3 inhibitors as maintenance therapy post allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia patients with FLT3 mutations: A meta‐analysis
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DOI: 10.1002/cam4.5480
Abstract: Acute myeloid leukemia (AML) patients with a Fms‐like tyrosine kinase 3 (FLT3) mutation have a high incidence of relapse despite allogeneic hematopoietic stem cell transplantation (allo‐HSCT) and a subsequent poor prognosis. FLT3 inhibitors (FLT3i) have… read more here.
Keywords: myeloid leukemia; allogeneic hematopoietic; stem cell; acute myeloid ... See more keywords
Outcomes associated with allogeneic hematopoietic stem cell transplantation for relapsed and refractory Hodgkin lymphoma in the era of novel agents
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DOI: 10.1002/cam4.5631
Abstract: Relapsed or refractory Hodgkin lymphoma (R/R HL) is a challenging disease with limited treatment options beyond brentuximab vedotin and checkpoint inhibitors. Herein we present the time‐trend analysis of R/R HL patients who received allogeneic hematopoietic… read more here.
Keywords: hodgkin lymphoma; allogeneic hematopoietic; refractory hodgkin; relapsed refractory ... See more keywords
The impact of intestinal microbiota in antithymocyte globulin–based myeloablative allogeneic hematopoietic cell transplantation
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DOI: 10.1002/cncr.34091
Abstract: The correlation between intestinal microbiota and clinical outcomes after allogeneic hematopoietic stem cell transplantation (allo‐HCT) has been reported in platforms with T‐cell depletion or postcyclophosphamide‐based graft‐vs‐host disease (GVHD) prophylaxis regimens. It is still unclear whether… read more here.
Keywords: cell; intestinal microbiota; allogeneic hematopoietic; cell transplantation ... See more keywords
Molecular disparity of HLA‐DPB1 is associated with the development of subsequent solid cancer after allogeneic hematopoietic stem cell transplantation
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DOI: 10.1002/cncr.34671
Abstract: An increased incidence of subsequent solid cancers (SSCs) has been reported in long‐term survivors of allogeneic hematopoietic stem cell transplantation (allo‐HSCT), and SSC is associated with inferior mortality and morbidity. Previous studies showed that the… read more here.
Keywords: allogeneic hematopoietic; stem cell; hla; subsequent solid ... See more keywords
Serum of interleukin‐6 and procalcitonin as early diagnostic markers for the identification of poor hematopoietic reconstitution following allogeneic hematopoietic stem cell transplantation
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DOI: 10.1002/cncr.35835
Abstract: Allogeneic hematopoietic stem cell transplantation (allo‐HSCT) remains a potential curative option for the treatment of various hematologic diseases. Poor hematopoietic reconstitution (PHR) is a common and serious complicating disease after allo‐HSCT. The authors conducted a… read more here.
Keywords: cell transplantation; hematopoietic stem; poor hematopoietic; stem cell ... See more keywords