Delivery of FK506-loaded PLGA nanoparticles prolongs cardiac allograft survival.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2019.118951
Abstract: In this study, FK506-loaded poly(lactide-co-glycolide) nanoparticles (PLGA-FK506-NPs) were developed using an O/W emulsion solvent evaporation method. The PLGA-FK506-NPs were observed to be monodispersed and spherical by transmission and scanning electron microscopy. The mean size and… read more here.
Keywords: fk506; allograft survival; plga fk506; fk506 nps ... See more keywords
Infusion of Lymphocytes Treated With 8-Methoxypsoralen and Ultraviolet A Light Induces CD19+IL-10+ Regulatory B Cells and Promotes Skin Allograft Survival.
Sign Up to like & getrecommendations! Published in 2018 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2018.04.066
Abstract: Extracorporeal photopheresis (ECP) represents an alternative to immunosuppression as a means of reducing rejection after thoracic organ transplantation. The mechanism by which ECP exerts its protective effects, until now, has remained elusive. Infusion of ECP-treated… read more here.
Keywords: allograft survival; infusion; skin allograft; regulatory cells ... See more keywords
Effects of Glycyrrhizic Acid in Licorice on Prolongation of Murine Cardiac Allograft Survival.
Sign Up to like & getrecommendations! Published in 2022 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2021.12.009
Abstract: Recent evidence has pointed to the promising benefits of using specific immunosuppressive herbal compounds to prolong transplant allograft survival. In this study, we investigated the effects of glycyrrhizic acid (GA), a major component of licorice,… read more here.
Keywords: allograft; mst days; allograft survival; glycyrrhizic acid ... See more keywords
Biomaterials-based immunomodulation enhances survival of murine vascularized composite allografts.
Sign Up to like & getrecommendations! Published in 2023 at "Biomaterials science"
DOI: 10.1039/d2bm01845d
Abstract: Vascularized composite allotransplantation (VCA) is a restorative option for patients suffering from severe tissue defects not amenable to conventional reconstruction. However, the toxicities associated with life-long multidrug immunosuppression to enable allograft survival and induce immune… read more here.
Keywords: vascularized composite; survival; pro regenerative; allograft survival ... See more keywords
Provision of Highly Specialized Aftercare by the Transplant Center Strongly Improves Patient and Allograft Survival in Long-term Follow-up After Kidney Transplantation
Sign Up to like & getrecommendations! Published in 2017 at "Transplantation"
DOI: 10.1097/01.tp.0000525012.58861.b9
Abstract: Background Despite rapid medical advancements in the field of transplantation over the last decades, mean kidney allograft survival remained at a standstill. If and to what extent a highly specialized, experienced, and up-to-date aftercare of… read more here.
Keywords: center; allograft survival; transplant center; ktrs ... See more keywords
PD22-08 PREDICTORS OF LONG-TERM RENAL ALLOGRAFT SURVIVAL AFTER SECOND KIDNEY TRANSPLANTATION
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Urology"
DOI: 10.1097/ju.0000000000000872.08
Abstract: INTRODUCTION AND OBJECTIVE: For patients who have undergone primary kidney transplant(PKT) and returned to dialysis, second kidney transplantation(SKT) offers improved quality of life and survival advantages. However, SKT is associated with increased immunologic and non-immunologic… read more here.
Keywords: allograft; renal allograft; long term; allograft survival ... See more keywords
Local Delivery of Adipose Stem Cell Promotes Allograft Survival in A Rat Hind Limb Model of Vascularized Composite Allotransplantation.
Sign Up to like & getrecommendations! Published in 2023 at "Plastic and reconstructive surgery"
DOI: 10.1097/prs.0000000000010510
Abstract: BACKGROUND Adipose stem cells (ASCs) are a promising cell-based immunotherapy due to their minimally invasive harvest, high yield, and immunomodulatory capacity. In this study, we investigated the effects of local vs. systemic ASC delivery on… read more here.
Keywords: cell; local delivery; adipose stem; allograft survival ... See more keywords
FOXP3 mRNA Profile Prognostic of Acute T Cell–mediated Rejection and Human Kidney Allograft Survival
Sign Up to like & getrecommendations! Published in 2020 at "Transplantation"
DOI: 10.1097/tp.0000000000003478
Abstract: Supplemental Digital Content is available in the text. Background. T cell–mediated rejection (TCMR) is the most frequent type of acute rejection and is associated with kidney allograft failure. Almost 40% of TCMR episodes are nonresponsive… read more here.
Keywords: allograft; kidney allograft; foxp3 mrna; cell ... See more keywords
Short‐term therapy with anti‐ICAM‐1 monoclonal antibody induced long‐term liver allograft survival in nonhuman primates
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Transplantation"
DOI: 10.1111/ajt.16486
Abstract: Tolerance induction remains challenging following liver transplantation and the long‐term use of immunosuppressants, especially calcineurin inhibitors, leads to serious complications. We aimed to test an alternative immunosuppressant, a chimeric anti‐ICAM‐1 monoclonal antibody, MD‐3, for improving… read more here.
Keywords: allograft survival; term; antibody; liver ... See more keywords
Mesenchymal stem cells augment regulatory T cell function via CD80‐mediated interactions and promote allograft survival
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Transplantation"
DOI: 10.1111/ajt.17001
Abstract: Mesenchymal stem cells (MSCs) and regulatory T cells (Tregs) both have been shown to modulate the alloimmune response and promote transplant survival. Mounting evidence suggests that MSCs augment Treg function, but the mechanisms underlying this… read more here.
Keywords: function; cd80; mesenchymal stem; allograft survival ... See more keywords
Administration of Interleukin-35-Conditioned Autologous Tolerogenic Dendritic Cells Prolong Allograft Survival After Heart Transplantation
Sign Up to like & getrecommendations! Published in 2018 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000493298
Abstract: Background/Aims: IL-35, a powerful suppressor of inflammation and autoimmunity, is primarily secreted by regulatory T cells (Tregs) and can, in turn, promote Treg differentiation. However, the precise effect of IL-35 on dendritic cells (DCs) remains… read more here.
Keywords: allograft survival; heart; dcs; allograft ... See more keywords