Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics
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DOI: 10.1016/j.celrep.2017.08.003
Abstract: Summary There is growing interest in using embryonic stem cell (ESC) and induced pluripotent stem cell (iPSC) derivatives for tissue regeneration. However, an increased understanding of human immune responses to stem cell-derived allografts is necessary… read more here.
Keywords: alloimmune responses; humanized mice; stem cell; pluripotent stem ... See more keywords
Effects of obesity and weight-loss surgery shift the microbiome and impact alloimmune responses
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DOI: 10.1097/mot.0000000000000920
Abstract: Purpose of review Obesity is a worldwide health problem with increasing rates in both children and adults. Bariatric surgery (BS) represents the only effective long-term treatment. Beneficial effects of BS may be mediated through shifts… read more here.
Keywords: responses effects; loss surgery; alloimmune responses; weight loss ... See more keywords
Alarmins and Their Receptors as Modulators and Indicators of Alloimmune Responses
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DOI: 10.1111/ajt.13887
Abstract: Cell damage and death releases alarmins, self‐derived immunomodulatory molecules that recruit and activate the immune system. Unfortunately, numerous processes critical to the transplantation of allogeneic materials result in the destruction of donor and recipient cells… read more here.
Keywords: alloimmune responses; indicators alloimmune; modulators indicators; transplantation ... See more keywords
Patterns of 1,748 Unique Human Alloimmune Responses Seen by Simple Machine Learning Algorithms
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DOI: 10.3389/fimmu.2020.01667
Abstract: Allele specific antibody response against the polymorphic system of HLA is the allogeneic response marker determining the immunological risk for graft acceptance before and after organ transplantation and therefore routinely studied during the patient's workup.… read more here.
Keywords: alloimmune responses; response; patterns 748; unique human ... See more keywords