A comparative analysis between proteasome and immunoproteasome inhibition in cellular and humoral alloimmunity
Sign Up to like & getrecommendations! Published in 2017 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2017.06.009
Abstract: Abstract Triggered by the successful administration of the proteasome inhibitor bortezomib in kidney transplant recipients with acute or chronic antibody‐mediated rejection, we evaluated the effect of the proteasome inhibitor CEP‐18770 and of the selective immunoproteasome… read more here.
Keywords: alloimmunity; inhibitor; proteasome; immunoproteasome ... See more keywords
March1-dependent modulation of donor MHC II on CD103+ dendritic cells mitigates alloimmunity
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-05572-z
Abstract: In transplantation, donor dendritic cells (do-DCs) initiate the alloimmune response either by direct interaction with host T cells or by transferring intact donor MHC to host DCs. However, how do-DCs can be targeted for improving… read more here.
Keywords: alloimmunity; dcs; cd103; donor mhc ... See more keywords
When rubber meets the road: how innate features of adaptive immune cells play critical roles in transplant alloimmunity.
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Organ Transplantation"
DOI: 10.1097/mot.0000000000000706
Abstract: PURPOSE OF REVIEW Studies on adaptive cells have largely focused on features that are specific to adaptive immunity. However, adaptive cells utilize innate cell features to modulate their responses, and this area of T and… read more here.
Keywords: innate; cell; innate features; alloimmunity ... See more keywords
Aging Affects the Role of Myeloid-Derived Suppressor Cells in Alloimmunity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.917972
Abstract: Myeloid-derived suppressor cells (MDSC) are defined as a group of myeloid cells with potent immunoregulatory functions that have been shown to be involved in a variety of immune-related diseases including infections, autoimmune disorders, and cancer.… read more here.
Keywords: alloimmunity; myeloid derived; suppressor cells; aging affects ... See more keywords