Ebselen oxide and derivatives are new allosteric HER2 inhibitors for HER2-positive cancers.
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DOI: 10.1002/1878-0261.13419
Abstract: Human epidermal growth factor receptor 2 (ErbB2/HER2) is a tyrosine kinase receptor that is overexpressed in 25% of primary human breast cancers, as well as in multiple other cancers. HER2-targeted therapies improved progression-free and overall… read more here.
Keywords: ebselen oxide; oxide derivatives; her2; new allosteric ... See more keywords