Elucidation of an Allosteric Mode of Action for a Thienopyrazole RORγt Inverse Agonist
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DOI: 10.1002/cmdc.202000044
Abstract: The demand for allosteric targeting of nuclear receptors is high, but examples are limited, and structural information is scarce. The retinoic acid‐related orphan receptor gamma t (RORγt) is an important transcriptional regulator for the differentiation… read more here.
Keywords: allosteric mode; elucidation allosteric; ror; thienopyrazole ror ... See more keywords