Allosteric targeting of the FFA2 receptor (GPR43) restores responsiveness of desensitized human neutrophils
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DOI: 10.1002/jlb.2a0720-432r
Abstract: The G protein‐coupled free fatty acid receptor 2 (FFA2R) is highly expressed on neutrophils and was previously described to regulate neutrophil activation. Allosteric targeting of G protein‐coupled receptors (GPCRs) is increasingly explored to create distinct… read more here.
Keywords: activation; receptor; allosteric targeting; human neutrophils ... See more keywords