Enantioselective Synthesis of α-Allyl Amino Esters via Hydrogen-Bond Donor Catalysis.
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DOI: 10.1021/jacs.9b05556
Abstract: We report a chiral-squaramide-catalyzed enantio- and diastereoselec-tive synthesis of α-allyl amino esters. The optimized protocol provides access to N-carbamoyl-protected amino esters via nucleophilic allyla-tion of readily accessible α-chloro glycinates. A variety of useful α-allyl amino… read more here.
Keywords: amino esters; esters via; allyl amino; synthesis allyl ... See more keywords
Crystal Structure and Molecular Conformational Studies of Allyl 6-Amino-5-cyano-4-(4-fluorophenyl)-2-methyl-4H-pyran-3-carboxylate
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DOI: 10.1134/s1063774519070101
Abstract: The allyl 6-amino-5-cyano-4-(4-fluorophenyl)-2-methyl-4H-pyran-3-carboxylate, C17H15FN2O3, compound adopts a triclinic crystal system with the sp. gr. $$P\bar {1}$$, Z = 2. The 4H-pyran ring adopts a boat conformation with their respective parameters (Q = 0.2384(26) A, θ… read more here.
Keywords: fluorophenyl methyl; cyano fluorophenyl; allyl amino; amino cyano ... See more keywords