Directed C8-H allylation of quinoline N-oxides with vinylcyclopropanes via sequential C-H/C-C activation.
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DOI: 10.1039/d2cc06646g
Abstract: The Rh(III)-catalyzed C8-allylation of quinoline N-oxides has been accomplished using vinylcyclopropanes as an allyl source with excellent diastereoselectivity at room temperature. The C-H/C-C activation, substrate scope and natural product mutation are the important practical features. read more here.
Keywords: quinoline oxides; directed allylation; activation; allylation quinoline ... See more keywords