Silica Support‐Enhanced Pd‐Catalyzed Allylation Using Allylic Alcohols
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DOI: 10.1002/cctc.201801097
Abstract: Although allylation using allylic alcohol is an environmentally‐friendly method because of water being the sole byproduct in such reactions, allylic alcohol is one of the most difficult allylating agents in Pd‐catalyzed allylation of nucleophiles. In… read more here.
Keywords: catalyzed allylation; allylic alcohols; using allylic; allylation using ... See more keywords
Iridium‐Catalyzed Asymmetric Isomerization of Primary Allylic Alcohols Using MaxPHOX Ligands: Experimental and Theoretical Study
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DOI: 10.1002/cctc.202000442
Abstract: The asymmetric isomerization of primary allylic alcohols to chiral aldehydes using iridium‐catalysts bearing P,N‐MaxPHOX ligands has been studied. These catalysts can be fine‐tuned as they present three different stereogenic centers to modulate both the reactivity… read more here.
Keywords: primary allylic; asymmetric isomerization; maxphox ligands; allylic alcohols ... See more keywords
Difluoroalkylation/1,2-aryl migration of allylic alcohols under transition metal-free conditions
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2021.153002
Abstract: Abstract A facile difluoroalkylation and 1,2-aryl migration reaction commencing from allylic alcohols and simple BrCF2COOEt was developed. This metal-free method offers chemists green and efficient access to important difluoro 1,5-dicarbonyl compounds in moderate to good… read more here.
Keywords: metal free; aryl migration; difluoroalkylation aryl; allylic alcohols ... See more keywords
Copper-catalyzed tandem radical amination/1,2-carbon migration of allylic alcohols: Direct access to α-quaternary-β-amino ketones
Sign Up to like & getrecommendations! Published in 2018 at "Chinese Journal of Catalysis"
DOI: 10.1016/s1872-2067(18)63028-1
Abstract: Abstract A novel nitrogen-centered radical-induced 1,2-carbon migration reaction of allylic alcohols has been developed. This method provides easy access to a variety of α-quaternary-β-amino ketones under mild reaction conditions. The reaction has a wide substrate… read more here.
Keywords: amino ketones; quaternary amino; carbon; allylic alcohols ... See more keywords
1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP)-Assisted Catalyst-Free Sulfonation of Allylic Alcohols with Sulfinyl Amides.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.1c04206
Abstract: A highly regioselective and catalyst-free sulfonation of allylic alcohols with sulfinyl amides has been realized. Such a mix-and-go procedure provides a convenient approach to synthetically various allylic sulfones under mild reaction conditions. Furthermore, this novel… read more here.
Keywords: allylic alcohols; sulfinyl amides; sulfonation; sulfonation allylic ... See more keywords
Ruthenium-Catalyzed 1,3-Aryl Redox Isomerization of Allylic Alcohols.
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DOI: 10.1021/acs.orglett.2c03410
Abstract: The isomerization of allylic alcohols to the corresponding carbonyl compounds is a well-established reaction in organic synthesis. However, 1,3-carbon migration is a quite challenging field, and thus transformation has remained elusive until now. Herein, we… read more here.
Keywords: ruthenium catalyzed; isomerization; aryl redox; allylic alcohols ... See more keywords
Lewis Base-Catalyzed Trifluoromethylsulfinylation of Allylic Alcohols: Stability-Oriented Divergent Synthesis.
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DOI: 10.1021/acs.orglett.2c04243
Abstract: A novel strategy is demonstrated for Lewis base-activated trifluoromethylsulfinylation of allylic alcohols. Controllable synthesis of structurally varied allylic trifluoromethanesulfones via sigmatropic rearrangements was performed, and trifluoromethanesulfinate esters were achieved. This metal-free, catalytic divergent transformation features… read more here.
Keywords: allylic alcohols; lewis base; trifluoromethylsulfinylation allylic;
Nickel-Catalyzed Direct Substitution of Allylic Alcohols with Nitriles: A General Tool for the Construction of Acyclic C2-Tertiary or Quaternary Benzyl Nitriles.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00323
Abstract: A nickel-catalyzed direct reaction of allylic alcohols with benzyl nitrile derivatives has been developed. The method provides an efficient route for the synthesis of nitriles bearing an α-tertiary or quaternary carbon center in good to… read more here.
Keywords: direct substitution; nickel catalyzed; allylic alcohols; catalyzed direct ... See more keywords
Aerobic C-C Bond Cleavage of Allylic Alcohols via Co-Catalyzed Hydrogen Atom Transfer.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00556
Abstract: A simple, efficient method has been developed for the CoIII-H-catalyzed aerobic C-C bond cleavage of tertiary allylic alcohols to access ketones. This novel approach presents excellent chemoselectivity, good functional group compatibility, and high yields. This… read more here.
Keywords: cleavage allylic; allylic alcohols; aerobic bond; bond cleavage ... See more keywords
Iridium-Catalyzed Enantioselective Allyl-Allyl Cross-Coupling of Racemic Allylic Alcohols with Allylboronates.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b03627
Abstract: Carreira's iridium-(P, olefin) phosphoramidite-based catalytic system that allows asymmetric allyl-allylboronate cross-coupling with high enantioselectivity is reported. This transformation tolerates a large variety of racemic branched allylic alcohols and allylboronate substrates. The utility of the coupling… read more here.
Keywords: iridium catalyzed; allyl; allylic alcohols; catalyzed enantioselective ... See more keywords
Molybdenum-Catalyzed Diastereoselective anti-Dihydroxylation of Secondary Allylic Alcohols.
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DOI: 10.1021/acs.orglett.9b00735
Abstract: In this protocol, we report a Mo-catalyzed anti-dihydroxylation of secondary allylic alcohols, providing a general method for the preparation of 1,2,3-triols bearing up to three continuous stereocenters with excellent diastereocontrol. The mechanistic studies reveal that… read more here.
Keywords: dihydroxylation secondary; dihydroxylation; allylic alcohols; molybdenum catalyzed ... See more keywords