Intermolecular amination of allylic and benzylic alcohols leads to effective inhibitions of acetylcholinesterase enzyme and carbonic anhydrase I and II isoenzymes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22173
Abstract: In this study, we aimed to determine the inhibition effects of novel synthesized sulfamates (2a–g), sulfonamides (3b–f), carbonyl sulfonamides (3h and i), and carbonyl sulfamates (4h and 4i), which were tested against two human cytosolic… read more here.
Keywords: carbonic anhydrase; inhibition; intermolecular amination; amination allylic ... See more keywords
Cobalt-catalyzed oxidative esterification of allylic/benzylic C(sp3)–H bonds
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.04.002
Abstract: A protocol for the cobalt-catalyzed oxidative esterification of allylic/benzylic C(sp3)–H bonds with carboxylic acids was developed in this work. Mechanistic studies revealed that C(sp3)–H bond activation in the hydrocarbon was the turnover-limiting step and the… read more here.
Keywords: esterification allylic; benzylic sp3; cobalt catalyzed; oxidative esterification ... See more keywords