Route to Chiral Tetrahydrofuran Acetals via Pd-Catalyzed Asymmetric Allylic Cycloaddition of Vinyl Epoxides with β-Keto Enol Ethers.
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DOI: 10.1021/acs.orglett.2c02437
Abstract: An efficient method for the synthesis of functionalized chiral tetrahydrofuran (THF) acetals via Pd-catalyzed asymmetric allylic cycloaddition has been developed. With a palladium catalyst coordinated by a chiral phosphine ligand, the protocol is enabled to… read more here.
Keywords: allylic cycloaddition; via catalyzed; acetals via; catalyzed asymmetric ... See more keywords