Optimization of the photodynamic inactivation of prions by a phthalocyanine photosensitizer: The crucial involvement of singlet oxygen.
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DOI: 10.1002/jbio.201800430
Abstract: Prion disorders are fatal neurodegenerative diseases caused by the autocatalytic conversion of a natively occurring prion protein (PrPC ) into its misfolded infectious form (PrPTSE ). The proven resistance of PrPTSE to common disinfection procedures… read more here.
Keywords: prion; singlet oxygen; inactivation; photodynamic inactivation ... See more keywords