PI3K-targeting strategy using alpelisib to enhance the antitumor effect of paclitaxel in human gastric cancer
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-68998-w
Abstract: PIK3CA mutations are frequently observed in various human cancers including gastric cancer (GC). This study was conducted to investigate the anti-tumor effects of alpelisib, a PI3K p110α-specific inhibitor, using preclinical models of GC. In addition,… read more here.
Keywords: combination; alpelisib paclitaxel; mutant cells; gastric cancer ... See more keywords