Oligomeric structure and chaperone-like activity of Drosophila melanogaster mitochondrial small heat shock protein Hsp22 and arginine mutants in the alpha-crystallin domain
Sign Up to like & getrecommendations! Published in 2017 at "Cell Stress and Chaperones"
DOI: 10.1007/s12192-017-0784-y
Abstract: The structure and chaperone function of DmHsp22WT, a small Hsp of Drosophila melanogaster localized within mitochondria were examined. Mutations of conserved arginine mutants within the alpha-crystallin domain (ACD) domain (R105G, R109G, and R110G) were introduced,… read more here.
Keywords: arginine mutants; alpha crystallin; drosophila melanogaster; structure chaperone ... See more keywords
Alpha B-crystallin C-802G polymorphism and colorectal cancer susceptibility and clinical outcome in Chinese population
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DOI: 10.1038/s41598-018-29589-y
Abstract: Colorectal cancer (CRC) is one of the most prevalent cancers worldwide and Alpha B-crystallin (CRYAB) protein has been identified as a prognostic biomarker for CRC. We evaluated CRYAB C-802G (rs14133)polymorphism in association with CRC risk… read more here.
Keywords: cryab 802g; colorectal cancer; chinese population; crc ... See more keywords
Alpha B‐crystallin promotes the invasion and metastasis of gastric cancer via NF‐κB‐induced epithelial‐mesenchymal transition
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DOI: 10.1111/jcmm.13602
Abstract: Alpha B‐crystallin (CRYAB) is overexpressed in a variety of cancers. However, little is known about its specific function and regulatory mechanism in gastric cancer. Here, we first explore the role of CRYAB in gastric cancer… read more here.
Keywords: cryab; gastric cancer; metastasis; cancer cells ... See more keywords
Cross-reactive EBNA1 immunity targets alpha-crystallin B and is associated with multiple sclerosis
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DOI: 10.1126/sciadv.adg3032
Abstract: Multiple sclerosis (MS) is an inflammatory disease of the central nervous system, for which Epstein-Barr virus (EBV) infection is a likely prerequisite. Due to the homology between Epstein-Barr nuclear antigen 1 (EBNA1) and alpha-crystallin B… read more here.
Keywords: cryab; alpha crystallin; ebna1; cross ... See more keywords